The Divine Healer's Vengeance

Murong Xi gave everything she had to putting Crown Prince Xuanyuan Hao on the throne. It had been a trap from the start, built by the prince together with her cousin Murong Yao. Once she was no longer useful she was locked away while pregnant, the whole Ducal Manor was put to death, and she died hating them. She wakes again at an earlier point in her own life and sets out to take it apart. She turns her aunt's and Murong Yao's schemes back on them, mends things with her younger brother Murong Ze, and wins over the old matriarch and her mother's Xiao relatives. She studies medical texts hard, and working under the name of an anonymous physician whose face nobody sees, she treats a plague outbreak and saves a commandery princess, so that her reputation grows without anyone tying it to her. Murong Yao keeps trying to frame her and keeps failing, which makes the Crown Prince suspicious of Murong Yao instead. During this she meets the Thirteenth Prince, Xuanyuan Chen, and they begin working against the Crown Prince together and grow attached to each other. To clear the field of rivals the Crown Prince poisons the emperor and lays the blame on the two of them. Murong Xi knows poisons well enough to see how it was done.